Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.
Product Name:
Human CFHR2 Recombinant Protein (RPES0951)
Product Code:
RPES0951
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Complement Factor H-Related Protein 2, FHR-2, DDESK59, H Factor-Like 3, H Factor-Like Protein 2, CFHR2, CFHL2, FHR2, HFL3
Accession:
P36980
Sequence:
Glu19-Lys270
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Complement Factor H-Related 2 is produced by our Mammalian expression system and the target gene encoding Glu19-Lys270 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
29.8 kDa
AP Mol Mass:
23-27 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
