Recombinant Human CFHR3 Protein (His Tag) (RPES3372)

SKU:
RPES3372
€142

Description

ELISA Kit Technical Manual

Recombinant Human CFHR3 Protein (His Tag)

Background:Complement factor H-related protein 3 is a protein that in humans is encoded by the CFHR3 gene. It is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains. CFHR3 is synthesized as a 330 amino acid precursor that contains an 18 amino acid signal peptide and a 312 amino acid mature chain. Human CFCR3 protein might be involved in complement regulation.
Name:Recombinant Human CFHR3 Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES3372
Synonyms:Complement factor H-related protein 3; FHR-3; DOWN16; H factor-like protein 3; CFHR3; CFHL3
Species:Human
Expression host:Human Cells
Sequence:Gln19-Glu330
Accession:Q02985
Mol Mass:36.4 kDa
AP Mol Mass:43-56 kDa
Tag:C-6His
Purity:> 95% as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per ?g as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Reconstitution:Please refer to the printed manual for detailed information.
UniProt Protein Function:Might be involved in complement regulation.
NCBI Summary:The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:Q02985
NCBI GenInfo Identifier:262231791
NCBI Gene ID:10878
NCBI Accession:NP_001160096.1
UniProt Related Accession:Q02985
Molecular Weight:
NCBI Full Name:complement factor H-related protein 3 isoform 2
NCBI Synonym Full Names:complement factor H related 3
NCBI Official Symbol:CFHR3  
NCBI Official Synonym Symbols:FHR3; HLF4; CFHL3; FHR-3; DOWN16  
NCBI Protein Information:complement factor H-related protein 3
UniProt Protein Name:Complement factor H-related protein 3
UniProt Synonym Protein Names:DOWN16; H factor-like protein 3
UniProt Gene Name:CFHR3  
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Additional Information

Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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