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Human CHST11/C4ST Recombinant Protein (RPES1674)

SKU:
RPES1674
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism
$648
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Description

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Human CHST11/C4ST Recombinant Protein

CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia.