Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE) and EGF-like repeats. CRELD2 is ubiquitously expressed in many tissues. CRELD2 may interact with CHRNA4 and regulate transport of ?4-β2 neuronal acetylcholine receptor. In addition, CRELD2 could be a novel mediator in regulating the onset and progression of various ER stress-associated diseases.
Product Name:
Human CRELD2 Recombinant Protein (RPES1878)
Product Code:
RPES1878
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Cysteine-Rich With EGF-Like Domain Protein 2, CRELD2
Accession:
Q6UXH1-2
Sequence:
Ala25-Leu321
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Cysteine-Rich with EGF-Like Domain Protein 2 is produced by our Mammalian expression system and the target gene encoding Ala25-Leu321 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
33.4 kDa
AP Mol Mass:
38 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS,5%Trehalose, pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
