D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.
Product Name:
Human DTD1 Recombinant Protein (RPES2521)
Product Code:
RPES2521
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-binding protein B,DUE-B,Histidyl-tRNA synthase-related,DTD1,C20orf88, DUEB, HARS2
Accession:
Q8TEA8
Sequence:
Met 1-Pro209
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human D-tyrosyl-tRNA(Tyr) deacylase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
24.5 kDa
AP Mol Mass:
30 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
