EDNRB/Endothelin B Receptor Recombinant Protein (RPES3856)
- SKU:
- RPES3856
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
EDNRB/Endothelin B Receptor Recombinant Protein
The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.
Product Name: | EDNRB/Endothelin B Receptor Recombinant Protein (RPES3856) |
Product Code: | RPES3856 |
Size: | 20µg |
Species: | Human |
Expressed Host: | HEK293 Cells |
Synonyms: | ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A |
Accession: | NP_000106.1 |
Sequence: | Met 1-Lys101 |
Fusion tag: | C-Fc |
Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
Protein Construction: | A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
Purity: | > 85 % as determined by reducing SDS-PAGE. |
Mol Mass: | 34.4 kDa |
AP Mol Mass: | 47.5 and 43.7 kDa |
Formulation: | Lyophilized from sterile PBS, pH 7.4 |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |