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EDNRB/Endothelin B Receptor Recombinant Protein (RPES3856)

SKU:
RPES3856
Product Type:
Recombinant Protein
Species:
Human
€540
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Description

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EDNRB/Endothelin B Receptor Recombinant Protein

The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.