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Human Ephrin-B2/EFNB2 Recombinant Protein (RPES3104)

SKU:
RPES3104
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cardiovascular
€117
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Description

system_update_altDatasheet

Human Ephrin-B2/EFNB2 Recombinant Protein

Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.