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Human Galectin-3/LGALS3 Recombinant Protein (RPES4635)

SKU:
RPES4635
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Developmental Biology
€212
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Description

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Human Galectin-3/LGALS3 Recombinant Protein

Galectin-3(LGALS3) is also known as Galactose-specific lectin 3; Mac-2 antigen; Carbohydrate-binding protein 35; Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma; and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth; as a result providing a new mechanism for tumor immune tolerance.