GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b.
Product Name:
Human GALNT2/GalNAc-T2 Recombinant Protein (RPES4125)
Product Code:
RPES4125
Size:
50 µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
GalNAc-T2
Accession:
NP_004472.1
Sequence:
Lys52-Gln571
Fusion tag:
N-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human GALNT2 (NP_004472.1) (Lys52-Gln571) was expressed with an N-terminal polyhistidine tag.
Purity:
(94.8+3.9) % as determined by reducing SDS-PAGE.
Mol Mass:
61.6 kDa
AP Mol Mass:
57-65 and 46 kDa
Formulation:
Lyophilized from sterile 25 mM Tris, 150 mM NaCl, 0.05% Brij-35, pH 7.5
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
