Human Gankyrin/PSDM10 Recombinant Protein (RPES4761)
- SKU:
- RPES4761
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
Frequently bought together:
Description
system_update_altDatasheet
Human Gankyrin/PSDM10 Recombinant Protein
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin is over-expressed in the majority of hepatocellular carcinomas. Gankyrin is involved in the regulation of retinoblastoma protein phosphorylation by CDK4 to enhance p53 ubiquitinylation by MDM2. Gankyrin is a protein that has been linked to the development of esophageal squamous cell carcinoma. Gankyrin has been shown to play an oncogenic function, particularly in the early phases of human epatocarcinogenesis. Human Gankyrin/PSDM10 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human Gankyrin/PSDM10 Recombinant Protein (RPES4761) |
| Product Code: | RPES4761 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | 26S Proteasome Non-ATPase Regulatory Subunit 10, 26S Proteasome Regulatory Subunit p28, Gankyrin, p28(GANK), PSMD10 |
| Accession: | O75832 |
| Sequence: | Met 1-Gly226 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Gankyrin is produced by our E.coli expression system and the target gene encoding Met1-Gly226 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.4 kDa |
| AP Mol Mass: | 26 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
