Human GAPDH Recombinant Protein (RPES2182)
- SKU:
- RPES2182
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
Frequently bought together:
Description
system_update_altDatasheet
Human GAPDH Recombinant Protein
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.
| Product Name: | Human GAPDH Recombinant Protein (RPES2182) |
| Product Code: | RPES2182 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | G3PD,GAPD,HEL-S-162eP |
| Accession: | P04406 |
| Sequence: | Met 1-Glu 335 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human GAPDH (P04406) (Met 1-Glu 335) was expressed, with a polyhistidine tag at the N-terminus. |
| Purity: | > 93 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 38 kDa |
| AP Mol Mass: | 38 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris, 30% glycerol, pH 7.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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