HMGB2 belongs to the non-histone chromosomal high mobility group family. HMGB2 is chromatin-associated and found throughout the nucleus of higher eukaryotic cells. In vitro research has shown that HMGB2 can bend DNA and form DNA rings successfully. In the final ligation step in DNA end-joining processes such as DNA double-strand breaks repair and V(D)J recombination, HMGB2 is also involved. The granzyme pathway, removal of Cdc6, and CDK-mediated phosphorylation are all HMGB2 related pathways. Human HMGB2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human HMGB2 Recombinant Protein (RPES0752)
Product Code:
RPES0752
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2
Accession:
P26583
Sequence:
Gly2-Glu209
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human High Mobility Group Protein B2 is produced by our Mammalian expression system and the target gene encoding Gly2-Glu209 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
25.1 kDa
AP Mol Mass:
28 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
