Interleukin-28B (cytokine Zcyto22/Interferon lambda-3/Interferon lambda-4/IFNL3/IFNL4/ZCYTO22/IL28B) is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. Human interleukin-28B has immunomodulatory properties and promotes MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA, which functions as a dimer. The ligand/receptor complex appears to signal via the Jak-STAT pathway. Human IFN-Lambda-3/IL-28B Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human IFN-Lambda-3/IL-28B Recombinant Protein (RPES1493)
Recombinant Human IFN-?3 is produced by our Mammalian expression system and the target gene encoding Val22-Val196 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
19.6 kDa
AP Mol Mass:
18 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;1mM EDTA;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
