null

Human IL18RAP/IL1R7 Recombinant Protein (RPES1133)

SKU:
RPES1133
Product Type:
Recombinant Protein
Species:
Human
€140
Frequently bought together:

Description

system_update_altDatasheet

Human IL18RAP/IL1R7 Recombinant Protein

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.