IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL-15. By cooperating with IL-15 and IL-18, which promote the production of interferon gamma by T-cells and natural killer cells. IL-21 dysregulation promotes the development of a variety of immunological diseases, including lupus, psoriasis, and chronic inflammatory disorders. Human Interleukin-21/IL-21 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Interleukin-21/IL-21 Recombinant Protein (RPES2209)
Product Code:
RPES2209
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Interleukin-21,IL-21, Za11, IL21
Accession:
Q9HBE4
Sequence:
Gln23-Ser155
Fusion tag:
Activity:
Immobilized Human IL-21 at 10µg/ml(100 ?l/well) can bind Human IL-2RG-Fc(Cat: PKSH033410).
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Interleukin-21 is produced by our E.coli expression system and the target gene encoding Gln23-Ser155 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.6 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
