Recombinant Human Interleukin-9/IL-9 Protein (His Tag) (RPES2644)

SKU:
RPES2644
€196

Description

ELISA Kit Technical Manual

Recombinant Human Interleukin-9/IL-9 Protein (His Tag)

Background:Interleukin-9 (IL-9) is a secreted protein that belongs to the IL-7/IL-9 family. IL-9 supports IL-2 independent and IL-4 independent growth of helper T-cells. IL-9 stimulates cell proliferation and prevents apoptosis. It functions through the IL-9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 has been identified as a candidate gene for asthma. IL-9 is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Name:Recombinant Human Interleukin-9/IL-9 Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES2644
Synonyms:Interleukin-9; IL-9; Cytokine P40; T-Cell Growth Factor P40; IL9
Species:Human
Expression host:Human Cells
Sequence:Glu19-Ile144
Accession:P15248
Mol Mass:15.2 kDa
AP Mol Mass:37 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Reconstitution:Please refer to the printed manual for detailed information.
UniProt Protein Function:IL9: Supports IL-2 independent and IL-4 independent growth of helper T-cells. Belongs to the IL-7/IL-9 family.
UniProt Protein Details:

Protein type:Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space

Molecular Function:growth factor activity; interleukin-9 receptor binding; cytokine activity

Biological Process: positive regulation of cell proliferation; immune response; inflammatory response; positive regulation of cell growth; positive regulation of interleukin-5 biosynthetic process

NCBI Summary:The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
UniProt Code:P15248
NCBI GenInfo Identifier:124362
NCBI Gene ID:3578
NCBI Accession:P15248.1
UniProt Related Accession:P15248
Molecular Weight:15kDa
NCBI Full Name:Interleukin-9
NCBI Synonym Full Names:interleukin 9
NCBI Official Symbol:IL9  
NCBI Official Synonym Symbols:P40; HP40; IL-9  
NCBI Protein Information:interleukin-9; cytokine P40; p40 cytokine; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40
UniProt Protein Name:Interleukin-9
UniProt Synonym Protein Names:Cytokine P40; T-cell growth factor P40
Protein Family:Interleukin
UniProt Gene Name:IL9  
UniProt Entry Name:IL9_HUMAN
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Additional Information

Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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