Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
Product Name:
Human KEL/CD238 Recombinant Protein (RPES2930)
Product Code:
RPES2930
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Kell blood group glycoprotein, CD238, KEL
Accession:
P23276
Sequence:
Asn68-Trp732
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Kelch-like protein 41 is produced by our Mammalian expression system and the target gene encoding Asn68-Trp732 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
78.4 kDa
AP Mol Mass:
85-120 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
