Recombinant Human LDH-A/LDHA Protein (His Tag) (RPES3651)

SKU:
RPES3651
€361

Description

ELISA Kit Technical Manual

Recombinant Human LDH-A/LDHA Protein (His Tag)

Background:L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
Name:Recombinant Human LDH-A/LDHA Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES3651
Synonyms:L-Lactate Dehydrogenase A Chain; LDH-A; Cell Proliferation-Inducing Gene 19 Protein; LDH Muscle Subunit; LDH-M; Renal Carcinoma Antigen NY-REN-59; LDHA
Species:Human
Expression host:E.coli
Sequence:Met 1-Phe332
Accession:P00338
Mol Mass:38.8 kDa
AP Mol Mass:37 kDa
Tag:N-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Formulation:Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 50% Glycerol, pH 8.0.
Reconstitution:Please refer to the printed manual for detailed information.
NCBI Summary:The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
UniProt Code:P00338
NCBI GenInfo Identifier:126047
NCBI Gene ID:3939
NCBI Accession:P00338.2
UniProt Secondary Accession:P00338,Q53G53, Q6IBM7, Q6ZNV1, Q9UDE8, Q9UDE9, B4DKQ2 B7Z5E3, D3DQY3, F8W819,
UniProt Related Accession:P00338
Molecular Weight:26,712 Da
NCBI Full Name:L-lactate dehydrogenase A chain
NCBI Synonym Full Names:lactate dehydrogenase A
NCBI Official Symbol:LDHA
NCBI Official Synonym Symbols:LDHM; GSD11; PIG19; HEL-S33P
NCBI Protein Information:L-lactate dehydrogenase A chain
UniProt Protein Name:L-lactate dehydrogenase A chain
UniProt Synonym Protein Names:Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
Protein Family:L-lactate dehydrogenase
UniProt Gene Name:LDHA
UniProt Entry Name:LDHA_HUMAN
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Additional Information

Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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