Vesicular integral-membrane protein VIP36 is also known as Glycoprotein GP36b; Lectin mannose-binding 2; Vesicular integral-membrane protein 36; LMAN2 and C5orf8. LMAN2 is widely expressed and contains one L-type lectin-like domain. LMAN2 binds high mannose type glycoproteins and may facilitate their sorting; trafficking and quality control. LMAN2 plays a role as an intracellular lectin in the early secretory pathway. LMAN2 interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. LMAN2 is also involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.
Product Name:
Human LMAN2/VIP36 Recombinant Protein (RPES2069)
Product Code:
RPES2069
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Vesicular Integral-Membrane Protein VIP36, Glycoprotein GP36b, Lectin Mannose-Binding 2, Vesicular Integral-Membrane Protein 36, VIP36, LMAN2, C5orf8
Accession:
Q12907
Sequence:
Asp45-Arg322
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Vesicular Integral-Membrane Protein VIP36 is produced by our Mammalian expression system and the target gene encoding Asp45-Arg322 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
32.7 kDa
AP Mol Mass:
33 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 50mM TrisHCl;10mM GSH;pH8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
