Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.
Product Name:
Human LRP12 Recombinant Protein (RPES3696)
Product Code:
RPES3696
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Low-Density Lipoprotein Receptor-Related Protein 12, LRP-12, Suppressor of Tumorigenicity 7 Protein, LRP12, ST7
Accession:
Q9Y561
Sequence:
Asn28-Ile488
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12 is produced by our Mammalian expression system and the target gene encoding Asn28-Ile488 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
52.5 kDa
AP Mol Mass:
68 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
