Osteoblast-Specific Factor OSF-2 (POSTN, Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. Periostin is a disulfide linked 90kDa bone adhesion protein secreted by osteoblasts and osteoblast-like cell lines and the protein is an attachment agent for osteoblasts. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.
Product Name:
Human Periostin/OSF-2 Recombinant Protein (RPES1663)
Recombinant Human Osteoblast Specific Factor 2 is produced by our Mammalian expression system and the target gene encoding Asn22-Gln836 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
85.6 kDa
AP Mol Mass:
85-90 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH8.0 .
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
