The enzyme PGMK1, also known as phosphoglycerate kinase 1, is a protein that converts 1,3-diphosphoglycerate to 3-phosphoglycerate in the glycolytic pathway. Phosphoglycerate kinase 1/PGK1 may also be a cofactor for polymerase α. The protein PGMK1/Phosphoglycerate kinase 1 is also secreted by tumor cells and has the ability to lower disulfide bridges in the serine protease plasmin, allowing angiostatin to be released from tumor blood vessels. A deficiency of PGK1/Phosphoglycerate kinase 1 (PGK1) causes a range of medical problems, including hemolytic anemia and neurological damage. Human PGK1/PGKA Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human PGK1/PGKA Recombinant Protein (RPES1880)
Product Code:
RPES1880
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Phosphoglycerate kinase 1,Cell migration-inducing gene 10 protein,Primer recognition protein 2,PGK1,PGKA
Accession:
P00558
Sequence:
Ser2-Ile417
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Phosphoglycerate kinase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Ile417 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
45.5 kDa
AP Mol Mass:
45 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,20% glycerol,pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
