PMVK Recombinant Protein (RPES1941)
- SKU:
- RPES1941
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Metabolism
Frequently bought together:
Description
system_update_altDatasheet
PMVK Recombinant Protein
Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
| Product Name: | PMVK Recombinant Protein (RPES1941) |
| Product Code: | RPES1941 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI |
| Accession: | Q15126 |
| Sequence: | Met 1-Leu192 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Phosphomevalonate Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu192 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.2 kDa |
| AP Mol Mass: | 26 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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