Human PI3/Elafin Recombinant Protein (RPES2748)
- SKU:
- RPES2748
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human PI3/Elafin Recombinant Protein
Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.
| Product Name: | Human PI3/Elafin Recombinant Protein (RPES2748) |
| Product Code: | RPES2748 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14 |
| Accession: | P19957 |
| Sequence: | Ala23-Gln117 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 11.0 kDa |
| AP Mol Mass: | 13-15 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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