Human PPIH Recombinant Protein (RPES1642)
- SKU:
- RPES1642
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
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Description
system_update_altDatasheet
Human PPIH Recombinant Protein
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
| Product Name: | Human PPIH Recombinant Protein (RPES1642) |
| Product Code: | RPES1642 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Peptidyl-Prolyl Cis-Trans Isomerase H, PPIase H, Rotamase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, U-snRNP-Associated Cyclophilin SnuCyp-20, USA-CYP, PPIH, CYP20, CYPH |
| Accession: | O43447 |
| Sequence: | Met 1-Met 177 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H is produced by our E.coli expression system and the target gene encoding Met1-Met177 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 21.4 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
