Profilin-II (PFN2) is ubiquitous protein which belongs to the profilin family. It binds to actin and modifies the cytoskeleton structure. At high concentrations, polymersizing actin is prevented because the reaction is negative, while it is encouraged at low levels. PFN2 is a ubiquitous actin monomer-binding protein. In response to extra cellular stimuli, it controls actin polymerization. PFN2 binds to PIP2; it inhibits the formation of IP3 and DG. Human Profilin-2/PFN2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Profilin-2/PFN2 Recombinant Protein (RPES2709)
Product Code:
RPES2709
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Profilin-II, PFN2, Profilin-2, PFL
Accession:
P35080
Sequence:
Met 1-Phe140
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Profilin-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe140 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.0 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris?150mM NaCl?pH 8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
