Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.
Product Name:
Progonadoliberin-2/GNRH2 Recombinant Protein (RPES2730)
Product Code:
RPES2730
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Progonadoliberin-2, Progonadoliberin II, Gonadoliberin-2, Gonadoliberin II, Gonadotropin-Releasing Hormone II, GnRH II, Luliberin II, Luteinizing Hormone-Releasing Hormone II, LH-RH II, GnRH-Associated Peptide 2, GnRH-Associated Peptide II, GNRH2
Accession:
O43555
Sequence:
Gln24-Val120
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Progonadoliberin-2 is produced by our Mammalian expression system and the target gene encoding Gln24-Val120 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
11.5 kDa
AP Mol Mass:
15-20 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
