The protein S100A4 encodes a calcium-binding protein with two EF-hand calcium-binding motifs that is part of the S100 family. S100 proteins are present in the cytoplasm and/or nucleus of a wide range of cells, and they regulate a variety of cellular activities including cell cycle progression and differentiation. Approximately 13 gene family members are included in the S100 family, all of which are concentrated on chromosome 1q21. Tubulin polymerization and motility are all enabled by this protein. S100A4 has been linked to tumor metastasis via chromosomal rearrangements and altered expression. Bile duct adenocarcinoma and small intestine adenocarcinoma are S100A4-related malignancies. Lipid, Ca and cAMP Signaling are just a few of the associated pathways to S100A4. Human S100A4 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human S100A4 Recombinant Protein (RPES0190)
Product Code:
RPES0190
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Protein S100-A4, Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, S100A4, CAPL, MTS1,18A2,42A,FSP1,P9KA,PEL98
Accession:
P26447
Sequence:
Met1-Lys101
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human S100A4 is produced by our E.coli expression system and the target gene encoding Met1-Lys101 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
12.6 kDa
AP Mol Mass:
13 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
