Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
Product Name:
Human SOD2/Mn-SOD Recombinant Protein (RPES5248)
Product Code:
RPES5248
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Superoxide Dismutase [Mn] Mitochondrial, SOD2
Accession:
P04179
Sequence:
Lys25-Lys222
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our Mammalian expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
23.2 kDa
AP Mol Mass:
25 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris;150mM NaCl;pH8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
