Recombinant Human SULT2A1 Protein (His Tag) (RPES2855)

SKU:
RPES2855
€289

Description

ELISA Kit Technical Manual

Recombinant Human SULT2A1 Protein (His Tag)

Background:Bile Salt Sulfotransferase (SULT2A1( is a cytosolic enzyme that belongs to the Sulfotransferase 1 family. SULT2A1 is primarily expressed in the liver and adrenal tissues, and to a lesser extent in the kidney. SULT2A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor, and it catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. SULT2A1 may have a role in the inherited adrenal androgen excess.
Name:Recombinant Human SULT2A1 Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES2855
Synonyms:Bile Salt Sulfotransferase; Dehydroepiandrosterone Sulfotransferase; DHEA-ST; Hydroxysteroid Sulfotransferase; HST; ST2; ST2A3; Sulfotransferase 2A1; ST2A1; SULT2A1; HST; STD;DHEA-ST;DHEAS;ST2A3
Species:Human
Expression host:E.coli
Sequence:Ser2-Glu285
Accession:Q06520
Mol Mass:35.2 kDa
AP Mol Mass:38 kDa
Tag:N-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Formulation:Supplied as a 0.2 um filtered solution of 20mM Tris, 100mM NaCl, pH 8.0.
Reconstitution:Please refer to the printed manual for detailed information.
UniProt Protein Function:SULT2A1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Belongs to the sulfotransferase 1 family.
UniProt Protein Details:

Protein type:EC 2.8.2.14; Transferase

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: cytosol

Molecular Function:sulfotransferase activity; protein binding; bile-salt sulfotransferase activity

Biological Process: steroid metabolic process; xenobiotic metabolic process; bile acid catabolic process; sulfation; digestion; cellular lipid metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process

NCBI Summary:This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010]
UniProt Code:Q06520
NCBI GenInfo Identifier:1711591
NCBI Gene ID:6822
NCBI Accession:Q06520.3
UniProt Related Accession:Q06520
Molecular Weight:285
NCBI Full Name:Bile salt sulfotransferase
NCBI Synonym Full Names:sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
NCBI Official Symbol:SULT2A1  
NCBI Official Synonym Symbols:HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST  
NCBI Protein Information:bile salt sulfotransferase; bile-salt sulfotranasferase 2A1; alcohol/hydroxysteroid sulfotransferase
UniProt Protein Name:Bile salt sulfotransferase
UniProt Synonym Protein Names:Dehydroepiandrosterone sulfotransferase; DHEA-ST; Hydroxysteroid Sulfotransferase; HST; ST2; ST2A3; Sulfotransferase 2A1; ST2A1
Protein Family:Bile salt sulfotransferase
UniProt Gene Name:SULT2A1  
UniProt Entry Name:ST2A1_HUMAN
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Additional Information

Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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