The TREM2 protein is a membrane receptor that binds to the TYRO protein tyrosine kinase binding protein and forms a receptor signalling complex. TREM2 is involved in the immune response and may be responsible for chronic inflammation by increasing continuous inflammatory cytokine synthesis. TREM2 gene mutation is linked to polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). semaphorin pathways and RET signalling are linked to TREM2. Human TREM2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human TREM2 Recombinant Protein (RPES1370)
Product Code:
RPES1370
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, TREM2,Trem2a,Trem2b,Trem2c
Accession:
Q9NZC2
Sequence:
His19-Ser174
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Triggering Receptor Expressed On Myeloid Cells 2 is produced by our Mammalian expression system and the target gene encoding His19-Ser174 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
18.3 kDa
AP Mol Mass:
28 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
