Description
| SKU: | RPCB2206 |
| Size: | 50 μg, 100 μg |
| Tag: | NO-Tag |
| Reactivity: | Human |
| Protein Description: | GAPDH is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer"s disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson"s disease, binds to GAPDH and displays neuroprotective actions. |
| Endotoxin: | < 0.01 EU/μg of the protein by LAL method. |
| Purity: | ≥ 90% as determined by reducing SDS-PAGE. |
| Formulation: | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Gene ID: | 2597 |
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P04406 |
