Human VAPB Recombinant Protein (RPES3595)
- SKU:
- RPES3595
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Frequently bought together:
Description
system_update_altDatasheet
Human VAPB Recombinant Protein
vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer; and heterodimer with VAPA. It also interacts with VAMP1; VAMP2; HCV NS5A; NS5B; ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is involved in cellular calcium homeostasis regulation.
| Product Name: | Human VAPB Recombinant Protein (RPES3595) |
| Product Code: | RPES3595 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Vesicle-associated membrane protein-associated protein B/C,VAMP-B/VAMP-C,VAMP-associated protein B/C,VAP-B/VAP-C |
| Accession: | O95292-1 |
| Sequence: | Ala2-Pro132 |
| Fusion tag: | C-6His |
| Activity: | Immobilized Human EphB2-Fc(Cat: PKSH032012) at 1µg/ml(100 ?l/well) can bind Human VAMPB-His. The ED50 of Human VAMPB-His is 5.179ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Vesicle-associated membrane protein-associated protein B is produced by our E.coli expression system and the target gene encoding Ala2-Pro132 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 16.0 kDa |
| AP Mol Mass: | 16 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
