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Human VCL/Vinculin Recombinant Protein (RPES2524)

SKU:
RPES2524
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
€300
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Description

system_update_altDatasheet

Human VCL/Vinculin Recombinant Protein

Vinculin is a focal adhesion and cytoskeletal protein that belongs to the Vinculin/alpha-Catenin family and is present in cells at cell-cell junctions and cell-extracellular matrix (ECM) adhesions. Vinculin is an Actin-binding protein and one of the components of the Actin-Linking Functional module, which detects and feels the extracellular environment's mechanical characteristics. Vinculin is also involved in the transfer, transduction, and regulation of mechanical force between the cytoskeleton and adhesion receptors. Vinculin has two structural states: an open (active) and a closed (inactive) form, which are controlled by conformational interactions between the head and tail domains. Vinculin is involved in the mechano-chemical signal transmission of cells by binding to a variety of focal adhesion or cytoskeletal proteins, and plays important roles in cell adhesion, extension, motion, proliferation and survival. Human VCL/Vinculin Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.