Human ZWINT Recombinant Protein (RPES3087)
- SKU:
- RPES3087
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Cycle
Frequently bought together:
Description
system_update_altDatasheet
Human ZWINT Recombinant Protein
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.
| Product Name: | Human ZWINT Recombinant Protein (RPES3087) |
| Product Code: | RPES3087 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT |
| Accession: | O95229 |
| Sequence: | Met 1-Pro277 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human ZW10 Interactor is produced by our E.coli expression system and the target gene encoding Met1-Pro277 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 33.4 kDa |
| AP Mol Mass: | 36 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
