The Recombinant IGF1R/CD221 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170040) against IGF1R. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, ICC/IF, FC and IP applications. It has been validated by WB analysis of HeLa, A431, A549, MCF7, HepG2, PC12, C6 and IF analysis of MCF-7. The target is localized to the cell membrane.
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunofluorescence analysis of MCF-7 cells labelling IGF- receptor beta. Nuclear DNA was labeled in blue with DAPI. Control: Secondary antibody only.
Western blot analysis of HeLa,A431,A549,MCF7,HepG2,PC12 and C6 cell lysates I using IGF1R/CD221 Antibody (RMEA0054) at a dilution of 1:1000. Observed-MW:95 kDa Calculated-MW:154 kDa