The Recombinant IKK alpha Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C333356) against IKK alpha. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Jurkat, Hela. The target is localized to the Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus.
