The Recombinant JAK1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110270) against JAK1. This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HeLa, K562. The target is localized to the Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.
Product Name:
Recombinant JAK1 Monoclonal Antibody
SKU:
AGEL5589
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
JAK, JAK 1, JAK 1A, JAK 1B, JAK-1, JAK1, JAK1A, JAK1B, Janus kinase, Janus kinase 1, Janus kinase 1 (a protein tyrosine kinase), JTK, JTK3, Tyrosine protein kinase JAK 1, Tyrosine protein kinase JAK1, Tyrosine-protein kinase JAK, Tyrosine-protein kinase JAK1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human JAK1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110270
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
JAK1
Conjugation:
Unconjugated
Observed MW:
133 kDa
Calculated MW:
133 kDa
Recommended Dilution:
IHC 1:100-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P23458
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.