Description
Recombinant JUNV Protein Z, N-His
Recombinant JUNV Protein Z, N-His is a recombinant protein expressed in E. coli, spanning Gly2-Pro94, with an N-terminal His tag. Predicted molecular weight: 38.58 kDa. Purity: >90%. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. RING finger protein Z is a ~10 kDa protein. Plays a crucial role in virion assembly and budding. For research use only.
Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.
| Product Name: | Recombinant JUNV Protein Z, N-His |
| SKU: | GXRP08768 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Junn mammarenavirus |
| Synonyms: | RING finger protein Z, Protein Z, Zinc-binding protein, Z |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly2-Pro94 |
| Calculated MW: | 38.58 kDa |
| UniProt: | Q6IVU5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
