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Recombinant Keap1 Monoclonal Antibody (AGEL5811)

Datasheet MSDS
SKU AGEL5811
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110496
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant Keap1 Monoclonal Antibody

The Recombinant Keap1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110496) against Keap1. This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HEK293 and IHC analysis of Mouse kidney. The target is localized to the cytoplasm, nucleus.

Product Name:Recombinant Keap1 Monoclonal Antibody
SKU:AGEL5811
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Cytosolic inhibitor of Nrf2, INrf, INrf 2, INrf2, Keap 1, KEAP-1, KEAP1, kelch like ECH associated protein 1, Kelch like family member 19, Kelch like protein 19, Kelch-like ECH-associated protein 1, Kelch-like protein 19, KIAA, KIAA0132, KLHL, KLHL 19, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human Keap1 protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C110496
Host:Rabbit
Isotype:Rabbit IgG
Target:Keap1
Conjugation:Unconjugated
Observed MW:60-70 kDa
Calculated MW:70 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:Q14145
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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