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Key Features

Recombinant LC3A Monoclonal Antibody (AGEL8669)

SKU AGEL8669
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133364
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant LC3A Monoclonal Antibody

The Recombinant LC3A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133364) against LC3A. LC3, also known as microtubule-associated protein 1 light chain 3 (MAP1LC3), is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A, LC3B, and LC3C. LC3 is first synthesized as pro-LC3, and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of A549, MCF-7, 293T, C2C12. The target is localized to the Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes.

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