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Key Features

Recombinant MCM5 Monoclonal Antibody (AGEL6526)

Datasheet MSDS
SKU AGEL6526
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC, IF
Host Species Rabbit
Clonality Monoclonal
Clone C111221
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant MCM5 Monoclonal Antibody

The Recombinant MCM5 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111221) against MCM5. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of Hela, JK, 4T1, IHC analysis of Human tonsil, Rat stomach and IF analysis of Hela. The target is localized to the chromosome, cytoplasm, nucleus.

Product Name:Recombinant MCM5 Monoclonal Antibody
SKU:AGEL6526
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:CDC, CDC 46, CDC46, CDC46 homolog, Cell division cycle, Cell division cycle 46, DNA replication licensing factor, DNA replication licensing factor MCM, DNA replication licensing factor MCM 5, DNA replication licensing factor MCM5, MCM, MCM 5, MCM5, MGC, MGC5315, Minichromosome maintenance complex component, Minichromosome maintenance complex component 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient protein 5, P1 CDC, P1 CDC46, P1-CDC, P1-CDC46
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human MCM5 fragment
Applications:WBIHCIF
Clonality:Recombinant Monoclonal
Clone No:C111221
Host:Rabbit
Isotype:Rabbit IgG
Target:MCM5
Conjugation:Unconjugated
Observed MW:82 kDa
Calculated MW:82 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-100; IF 1:50
UniProt:P33992
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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