The Recombinant MHC Class I Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C221224) against MHC Class I. Antigen-presenting major histocompatibility complex class I (MHCI) molecule. In complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by T cell receptor (TCR) on MHCI -restricted CD8-positive T cells, guiding antigen-specific T cell immune response to eliminate infected or transformed cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Raji, THP-1, A549, A431 and IHC analysis of Human liver, Mouse liver, Rat liver. The target is localized to the membrane.
Product Name:
Recombinant MHC Class I Monoclonal Antibody
SKU:
AGEL6529
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
HLA-A, HLA-A protein, HLAA, MHC class I antigen A, MHC leukocyte antigen
Reactivity:
Human, Mouse
Immunogen:
Recombinant human MHC Class I fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C221224
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MHC Class I
Conjugation:
Unconjugated
Observed MW:
40 kDa
Calculated MW:
41 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:100
UniProt:
P04439
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
