The Recombinant Mitofusin-2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110969) against Mitofusin-2. This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HEK293. The target is localized to the mitochondrion outer membrane.
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
O95140
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant Mitofusin-2 Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: HEK293 whole cell lysate. Observed-MW:86 kDa Calculated-MW:86 kDa
![Anti-Mitofusin 2 [R56-8V-9] Monoclonal Antibody (AGMB01871)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/273160/679642/anti-mitofusin-2-r56-8v-9-monoclonal-antibody-agmb01871__88681.1773039609.jpg?c=2 "Anti-Mitofusin 2 [R56-8V-9] Monoclonal Antibody (AGMB01871)")