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Key Features

Recombinant MLH1 Monoclonal Antibody (RMEA3369)

Datasheet MSDS
SKU RMEA3369
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IF
Host Species Rabbit
Clonality Monoclonal
Clone C173369
Conjugate Unconjugated
€349 - €479

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Description

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Recombinant MLH1 Monoclonal Antibody

The Recombinant MLH1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C173369) against MLH1. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IF applications. It has been validated by WB analysis of K562, C6, 3T3, Hela and IF analysis of Hela cells. The target is localized to the nucleus.

Product Name:Recombinant MLH1 Monoclonal Antibody
SKU:RMEA3369
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:1, COCA 2, COCA2, colon cancer, DNA mismatch repair protein Mlh1, E. coli, FCC 2, FCC2, hMLH 1, hMLH1, HNPCC, HNPCC 2, HNPCC2, homolog of, MGC5172, MLH 1, MLH1, MutL, MutL homolog 1, MutL homolog 1 (E. coli), MutL homolog 1 colon cancer nonpolyposis type 2, MutL protein homolog 1, nonpolyposis type 2, nonpolyposis type 2 (E. coli)
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human MLH1
Applications:WBIF
Clonality:Recombinant Monoclonal
Clone No:C173369
Host:Rabbit
Isotype:Rabbit IgG
Target:MLH1
Conjugation:Unconjugated
Observed MW:85 kDa
Calculated MW:85 kDa
Recommended Dilution:WB 1:1000-2000; IF 1:50-100
UniProt:P40692
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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