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Key Features

Recombinant MLKL Monoclonal Antibody (AGEL5659)

Datasheet MSDS
SKU AGEL5659
Product Type Antibody
Reactivity Human, Mouse, Rat, Chicken
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110340
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant MLKL Monoclonal Antibody

The Recombinant MLKL Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110340) against MLKL. This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse, Rat and Chicken samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm.

Product Name:Recombinant MLKL Monoclonal Antibody
SKU:AGEL5659
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:9130019I15Rik, FLJ34389, hMLKL, Mixed lineage kinase domain like, Mixed lineage kinase domain like protein, Mixed lineage kinase domain like pseudokinase, Mixed lineage kinase domain-like protein, MLKL
Reactivity:Human, Mouse, Rat, Chicken
Immunogen:Recombinant Human MLKL protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C110340
Host:Rabbit
Isotype:Rabbit IgG
Target:MLKL
Conjugation:Unconjugated
Observed MW:55 kDa
Calculated MW:55 kDa
Recommended Dilution:IHC 1:1000-4000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:Q8NB16
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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