The Recombinant MMP9 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C411001) against MMP9. Cleavage of gelatin types I and V and collagen types IV and V., cofactor:Binds 2 zinc ions per subunit., cofactor:Binds 3 calcium ions per subunit., disease:Defects in MMP9 may be a cause of susceptibility to lumbar disk herniation (LDH) [MIM:603932]. LDH is the predominant cause of low-back pain and unilateral leg pain., domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme., enzyme regulation:Inhibited by histatin-3 1/24 (histatin-5)., May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Mouse lung. The target is localized to the membranous.
Product Name:
Recombinant MMP9 Monoclonal Antibody
SKU:
AGEL6307
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
92 kDa gelatinase, 92 kDa type IV collagenase, 92kDa Type IV Collagenase, AW743869, B/MMP, B/MMP9, Clg4b, Gelatinase B, GELB, IBP, IBP6, Igfbp, IGFBP6, MANDP, MANDP2, Matrix metalloproteinase, Matrix metalloproteinase-9, MMP-9, Mmp9, pro-MMP-9
Reactivity:
Mouse, Rat
Immunogen:
Recombinant Mouse MMP9 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C411001
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MMP9
Conjugation:
Unconjugated
Observed MW:
80 kDa-92 kDa
Calculated MW:
78 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:500-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P41245
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.