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Key Features

Recombinant MMP9 Monoclonal Antibody (AGEL6307)

SKU AGEL6307
Product Type Antibody
Reactivity Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C411001
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant MMP9 Monoclonal Antibody

The Recombinant MMP9 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C411001) against MMP9. Cleavage of gelatin types I and V and collagen types IV and V., cofactor:Binds 2 zinc ions per subunit., cofactor:Binds 3 calcium ions per subunit., disease:Defects in MMP9 may be a cause of susceptibility to lumbar disk herniation (LDH) [MIM:603932]. LDH is the predominant cause of low-back pain and unilateral leg pain., domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme., enzyme regulation:Inhibited by histatin-3 1/24 (histatin-5)., May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Mouse lung. The target is localized to the membranous.

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