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Mouse Cathepsin S/CTSS Recombinant Protein (RPES4953)

SKU:
RPES4953
Product Type:
Recombinant Protein
Species:
Mouse
€300
Frequently bought together:

Description

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Mouse Cathepsin S/CTSS Recombinant Protein

Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of AlzheimerÂ’s disease (AD) and Down Syndrome (DS).