Recombinant Mouse CCL21/CCL21a Protein (RPES5129)
- SKU:
- RPES5129
Description
Recombinant Mouse CCL21/CCL21a Protein
| Background: | C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs. | ||||||
| Name: | Recombinant Mouse CCL21/CCL21a Protein | ||||||
| Size: | 10µg | ||||||
| Assay Genie SKU: | RPES5129 | ||||||
| Synonyms: | C-C Motif Chemokine 21a; 6Ckine; Beta-Chemokine Exodus-2; Small-Inducible Cytokine A21a; Thymus-Derived Chemotactic Agent 4; TCA4; Ccl21a; Scya21; Scya21a | ||||||
| Species: | Mouse | ||||||
| Expression host: | E.coli | ||||||
| Sequence: | Ser24-Gly133 | ||||||
| Accession: | P84444 | ||||||
| Mol Mass: | 12.0 kDa | ||||||
| AP Mol Mass: | 16 kDa | ||||||
| Tag: | |||||||
| Purity: | > 95 % as determined by SDS-PAGE | ||||||
| Endotoxin: | < 1.0 EU per µg as determined by the LAL method. | ||||||
| Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months. | ||||||
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. | ||||||
| Formulation: | Lyophilized from a 0.2 um filtered solution of 20mM PB?150mM NaCl,pH7.4. | ||||||
| Reconstitution: | Please refer to the printed manual for detailed information. | View AllClose
Product type: |
Recombinant Protein |
Host species: |
E.coli |
Reactivity: |
Mouse |
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