Mouse Interleukin-1 (IL-1) designates two proteins, IL-1? and IL-1β, which are the products of distinct genes, but recognize the same cell surface receptors. IL-1? and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.
Product Name:
Mouse ILA/IL Alpha Recombinant Protein (RPES1705)
Product Code:
RPES1705
Size:
20 µg
Species:
Mouse
Expressed Host:
E.coli
Synonyms:
Interleukin-1 Alpha, IL-1 Alpha, Il1a
Accession:
P01582
Sequence:
Ser115-Ser270
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Interleukin-1 alpha is produced by our E.coli expression system and the target gene encoding Ser115-Ser270 is expressed.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
18.0 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 50mM TrisHCl, 200mM NaCl, pH 8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
